Listen free for 30 days

Listen with offer

Sample

£0.00 for first 30 days

Pick 1 audiobook a month from our unmatched collection - including bestsellers and new releases.
Listen all you want to thousands of included audiobooks, Originals, celeb exclusives, and podcasts.
Access exclusive sales and deals.
£7.99/month after 30 days. Renews automatically. See here for eligibility.

Lifespan

By: Dr David A. Sinclair, Matthew D. LaPlante
Narrated by: Dr David A. Sinclair
Try for £0.00

£7.99/month after 30 days. Renews automatically. See here for eligibility.

Buy Now for £12.99

Buy Now for £12.99

Pay using card ending in
By completing your purchase, you agree to Audible's Conditions of Use and authorise Audible to charge your designated card or any other card on file. Please see our Privacy Notice, Cookies Notice and Interest-based Ads Notice.
activate_samplebutton_t1

Listeners also enjoyed...

A Crack in Creation cover art
The Science and Technology of Growing Young cover art
Mitochondria and the Future of Medicine cover art
The Carnivore Code cover art
The Comfort Crisis cover art
The Lucky Years cover art
Get Out of Your Head cover art
The Blue Zones cover art
The China Study, Revised and Expanded Edition cover art
Lies My Doctor Told Me cover art
The Story of the Human Body cover art
The End of Illness cover art
Age Later cover art
Whole cover art
The Plant Paradox cover art
Hacking Darwin cover art

Summary

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help listeners live younger, longer.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease – it is inevitable.

But what if everything you think you know about ageing is wrong?

What if ageing is a disease? And that disease is curable.

In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan – he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick – a circuit designed to halt reproduction in order to repair damage to the genome –has enabled earth’s early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.

But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Listeners will discover how a few simple lifestyle changes – like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy – can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like – and what will need to change – when we are all living well to 120 or more.

Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. LIFESPAN is destined to be the biggest book on genes, biology, and longevity of this decade.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2019 Dr David A. Sinclair (P)2019 HarperCollins Publishers Limited

Critic reviews

‘If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant.’ – Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and #1 New York Times bestselling author

‘This is the most visionary book about aging I have ever read. Seize the day–and seize this book!’ – Dean Ornish, MD, founder & president, Preventive Medicine Research Institute, and New York Times bestselling author of UnDo It!

‘In this insightful and provocative book that asks questions about how we age, and whether humans can overcome decay and degeneration, Sinclair grapples with some of the most fundamental questions around the science of aging. The result is an elegant and exciting book that deserves to be read broadly and deeply.’ – Siddhartha Mukherjee, Pulitzer Prize–winning and #1 New York Times bestselling author

What listeners say about Lifespan

Average customer ratings
Overall
  • 4.5 out of 5 stars
  • 5 Stars
    1,335
  • 4 Stars
    265
  • 3 Stars
    71
  • 2 Stars
    28
  • 1 Stars
    14
Performance
  • 4.5 out of 5 stars
  • 5 Stars
    1,164
  • 4 Stars
    203
  • 3 Stars
    60
  • 2 Stars
    21
  • 1 Stars
    8
Story
  • 4.5 out of 5 stars
  • 5 Stars
    1,105
  • 4 Stars
    225
  • 3 Stars
    75
  • 2 Stars
    23
  • 1 Stars
    16

Reviews - Please select the tabs below to change the source of reviews.

Sort by:
Filter by:
  • Overall
    4 out of 5 stars
  • Performance
    4 out of 5 stars
  • Story
    3 out of 5 stars

Heady aspirations.

Life extension research and it's implications.
Personally I enjoyed the science parts at the beginning of the book. The implications of longer lives felt like it was turning into a sermon and went on too long for me.
On the whole exciting science though and Dr Sinclair definitely has the enthusiastic voice & experience to rally the charge.

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

7 people found this helpful

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars

Inspiring.

Couldn’t have asked for a more coherent case for immortality as a utilitarian answer for civilisations woes.

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars

Enlightment!

A call to action to change the way we live and will live, and you can contribute to it starting today. Exquisite, highly provocative, very well explained and inspiring. Highly recommended!!

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars

Comprehensive and competent rewiew of literature

I found this very accessible, relevant to the study I was engaged in and highly recommend it

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    4 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars

Informative

I find this book informative. It helps me a lot in understanding aging and health. Watching my grandfather age, I know i don’t want the same kind of old age. And if a healthier, more active old age is possible, it is the best news for us. However, I felt suspicious, as I listened, of the author’s optimism sometimes of what humans will do with the treatments for aging.

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars

mind blowing

I have lost words to describe this book.
out of the ordinary. Challenges my biases and preconceptions. A truly revolutionary book backed by real science. Marvellous. Don't buy if you don't want to try and live longer and see your grandkids...and their grandkids.

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    4 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    3 out of 5 stars

You should probably learn a thing or two about longevity

Very interesting topic and David Sinclair does a great job in his narration.

The average listener should prepare to feel dumb at times - a lot of the research (especially in the middle of the book) went over my head.

That said, longevity is extremely interesting and I’ll implement most of the practices taught in the book even though I’ll have to return to the book in a year or two to fully grasp it.

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    4 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    4 out of 5 stars

Opens a new perspective

A great thought provoking book that opens a new perspective. Certainly worth reading / listening to.

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars

So good that I can recommend to everyone

This is really fantastic book with totally different views on our life’s decisions and healthy
Strongly recommend to everyone who wants to live above 100 years 💪
Thank you authors

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars

A Must Read

Interesting, scientific and inspiring. The book gives hope for the future and made me think carefully about aging and the definition of it. great book with zero fluff

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!