Joyce Lu from the University of Ottawa interviews Dr. Céline Aguer. Dr. Aguer is an assistant professor at McGill University in the Department of Physiology and principal investigator in her muscle metabolism laboratory at the Institut du Savoir Montfort in Ottawa. In this episode, Dr. Aguer shares her research on how bisphenol A (BPA), an environmental pollutant, disrupts muscle metabolism. This episode also features additional commentary by Dr. Ella Atlas, adjunct professor at the Department of Biochemistry, Microbioloy and Immunology and Health Canada Research Scientist on environmental pollutants.

Learn more

Dr. Céline Aguer: https://www.uottawa.ca/faculty-medicine/dr-celine-aguer
Dr. Ella Atlas: https://www.uottawa.ca/faculty-medicine/dr-ella-atlas

0:16 | BEaTS, Host introduction, and Background information.
0:55 | Introduction to Dr. Aguer
1:26 | How Dr. Aguer started research on pollutants and muscle metabolism,
2:54 | Current issues with BPA exposure and why studying BPA is important?
5:51 | Special Guest Dr. Ella Atlas Introduction
6:11 | Dr. Atlas' insights on BPA alternatives and avoidance
8:05 | How BPA can cause insulin resistance in muscle cells
11:15 | Other potential health impacts of BPA exposure
12:22 | Future Studies with the Aguer Lab
14:08 | Closing Remarks

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Joyce Lu (Podcast Host), Emily Wood (Writer/Editor), Ernest Ngou (Audio Master), Angela Wang (Producer)

Sahib Moga from the University of Ottawa interviews Dr. Jean-François Couture. Dr. Couture is a Full Professor and Chair in the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. He has published over 90 papers in prestigious journals and is a leading structural biology and epigenetics expert. In this episode, Dr. Couture shares his research on the role of a non-canonical zinc finger in stabilizing Cfp1’s integration into the H3K4 methyltransferase complex COMPASS and its implications for epigenetic signaling and cancer biology.

Learn more: http://jfclab.ca/

0:05 | BEaTS and host introduction
1:00 | Introduction to Dr. Couture
1:58 | Introduction to epigenetics and structural biology
5: 55 | COMPASS complex and its role
8:14 | Novel zinc finger discovery
12:20 | Future treatments and drug development
13:15 | Conclusion

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Daniel Nguyen (Producer), Sahib Moga (Host), Ryan Zammar (Content Writer), Francesco Cortese (Post-Production)

Iman Kashif from the University of Ottawa interviewed Dr. Barbara Vanderhyden, a senior scientist in ovarian cancer research and a professor at the University of Ottawa. In this insightful episode, Dr. Vanderhyden discusses her groundbreaking research pertaining to how immune regulator NLRC5 can reshape the tumor microenvironment and increase T-cell reactivity to better recognize and respond to cancer cells. She explains the mechanisms of immune evasion in ovarian cancer and discusses how her work could pave the way for novel therapeutic approaches.

Learn more: https://www.ohri.ca/profile/vanderhydenlab/profile

1:47 | Immune Evasion and NLRC5.
4:49 | Clinical Applications of NLRC5.
6:28 | Combination Therapy with NLRC5.
9:23 | Tumor Adaptation Challenges.
12:26 | Advice for Early Career Professionals.

Music Credit/Copyright information: Copyright free, Youtube video: “DEATH NOTE - L THEME SONG (RIFTI BEATS REMIX) [No Copyright Music]”. Account: Kingdom Power Music. Published January 18, 2021. https://www.youtube.com/watch?v=AkFHNQELp3Y&ab_channel=KingdomPowerMusic

Iman Kashif (Host, Audio Master), Jacqueline Aoun (Producer), Aaya Mahdi (Content Writer), Shreya Padhy (Content Writer)