Possible

By: Reid Hoffman
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  • Summary

  • What if, in the future, everything breaks humanity's way? Possible is an award-winning, weekly podcast that sketches out the brightest version of the future—and what it will take to get there. Hosts Reid Hoffman and Aria Finger explore what’s possible with forward-thinking leaders, deep thinkers, and ambitious builders across many fields, such as technology, art, education and healthcare. These conversations center on the ways technology—and, in particular, AI—is shaping the future. In episodes, AI tools such as OpenAI’s GPT-4 and Inflection’s Pi are at work, offering informational asides, prompting guests, or demoing what they can do. Lastly, between guest episodes, Aria interviews her co-host Reid on his latest takes on what’s possible if we use technology—and our collective effort—effectively.
    Reid Hoffman 2023
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Episodes
  • Reid riffs on his personal history with AI

    Reid riffs on his personal history with AI
    Sep 11 2024
    Reid reflects on his early exposure to AI as an undergraduate at Stanford and on navigating the space between academia and industry. Plus, he and Aria discuss human outcomes of technology—and how human-centered technologists such as Fei-Fei Li, Mustafa Suleyman, and Kevin Scott have helped him keep those outcomes top of mind. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    11 mins
  • Daphne Koller on drug discovery and AI

    Daphne Koller on drug discovery and AI
    Sep 4 2024
    How can scientists leverage AI and machine learning to more effectively research, develop, and deliver new drugs? This week, Reid and Aria talk drug development with renowned computer scientist and executive Dr. Daphne Koller, whose company, insitro, uses machine learning to improve the quality and speed of drug discovery. She addresses several ways AI and ML are already being used to redefine diseases and create better therapeutic interventions. Plus, she shares her experience transitioning from academia to industry. Read the transcript of this episode here: https://www.possible.fm/podcasts/dkoller For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 00:01: Cold open 00:43: Hellos and intros 3:20: Early involvement in AI 5:00: Overview of drug discovery and its evolution over the last five years 7:50: AI and machine learning impact on biology and drug development 9:09: Pi aside defining AlphaFold 11:37: Areas of acceleration and opportunity in AI and drug discovery 17:21: Synthetic data 21:21: AI implications on therapeutic hypotheses 23:54: Personalized vs. precision medicine 27:04: Closing the data feedback loop 30:31: Exciting announcements 34:24: Privacy and data 36:41: GPT-4 story 38:48: Stuart Russell’s comments on the applications of Koller’s thesis 43:36: AI as a moving target 47:24: How can academia and industry positively impact society and humanity 51:58: insitro’s culture 54:18: - Rapid-fire questions Select mentions: Not the End of the World: How We Can Be the First Generation to build a Sustainable Planet by Hannah Ritchie Stuart Russell Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    1 hr
  • Reid riffs on the future of human connectivity

    Reid riffs on the future of human connectivity
    Aug 28 2024
    This week, Reid veers toward science fiction, tackling big questions including: Is a single mentally-linked network in our future? Can and should humans create other sentient beings? Select mentions: David Brin
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    9 mins

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