Showing titles in Genetics

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.

DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction.

In From Darwin to Derrida, evolutionary biologist David Haig explains how a physical world of matter in motion gave rise to a living world of purpose and meaning. Natural selection, a process without purpose, gives rise to purposeful beings who find meaning in the world. The key to this, Haig proposes, is the origin of mutable “texts”―genes―that preserve a record of what has worked in the world. These texts become the specifications for the intricate mechanisms of living beings.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Brian and Deborah Charlesworth provide a clear and concise summary of the process of evolution by natural selection, and how natural selection gives rise to adaptations and eventually, over many generations, to new species. They introduce the central concepts of the field of evolutionary biology, as they have developed since Darwin and Wallace on the subject, over 140 years ago, and discuss some of the remaining questions regarding processes.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

Red is a brilliantly told, captivating history of red hair throughout the ages. An audiobook that breaks new ground, dispels myths, and reinforces the special nature of being a redhead, with a look at multiple disciplines, including science, religion, politics, feminism and sexuality, literature, and art. With an obsessive fascination that is as contagious as it is compelling, author Jacky Colliss Harvey (herself a redhead) begins her exploration of red hair in prehistory and traces the redhead gene as it made its way out of Africa with the early human diaspora.

One of the biggest discoveries in physics, the quest for the Higgs boson demonstrates the value of a good theory. In July 2012, a Higgs-like particle was found near the energies scientists predicted. Now, armed with better evidence and better questions, the scientific process continues. In this audiobook, we’ve gathered our best reporting to explain that process - the theories, the search, the discovery, and the ongoing questions.

With so much variation that can be handed down genetically, for better or worse, the way we understand our biology holds huge importance for how we understand our world and one another, including the biggest questions of our day, such as social inequality. Eye-opening and profound, Adaptable is a revolutionary reappraisal of an overlooked science.

Po Bronson and Arvind Gupta, venture capitalists from Silicon Valley, take everyday news headlines and decode them, leading us on a journey through their unique and highly entertaining view of the world. Each chapter is prefaced with a real-world headline from today's chaotic news cycle: dying bees. Rogue planets. Beyond Meat. Glaciers melting. Bronson and Gupta decipher what's really going on behind these headlines, and why.

In The Genetic Lottery, Harden introduces listeners to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society.

Already technology enables parents to select some genetic traits for their children, and soon it will be possible to begin to shape ourselves as a species. Countering loud cries of alarm, bioethics expert Ronald Green explains why our fears about genetic engineering are overblown and how we can move forward responsibly to create a better future.

Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?

Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

In The Lost Family, journalist Libby Copeland investigates what happens when we embark on a vast social experiment with little understanding of the ramifications. Copeland explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.