Genetic Engineering Science

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

There are rare moments in time when we make choices that irreversibly change the world, and our lives, forever. Today is one of those moments. Scientists, engineers and philosophers alike warn us that without a radical shift in our thinking, we are on track to be the last generation of pure humans that the world will know. Within a single generation we will devolve into a hybrid species of synthetic bodies, Artificial Intelligence (AI), and computer chips that limit our ability to think, to love, and to adapt to the conditions of the emerging world in a healthy way.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

In 1994 Professor Bryan Sykes, a leading world authority on DNA and human evolution, was called in to examine the frozen remains of a man trapped in glacial ice in northern Italy. News of both the Ice Man's discovery and his age, which was put at over 5,000 years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative?

From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

Ships are sinking for no apparent reason, carrying hundreds to a dark underwater grave. Strange fireballs race through the sky above the deepest trenches of the oceans. Something is about to show itself, something terrible and alien, a force capable of causing global catastrophe.

Leigh grew up in Rotterdam, drawn to the waterfront as a refuge from her unhappy home life and volatile father. Enchanted by the marine world of her childhood, she excels in postgraduate research on ancient algae. When an unfathomable vent appears in the mid-Atlantic floor, Leigh joins the investigating team; what she finds there will change her life forever. Around the same time, a trio of engineers, unknown to each other, make a seismic breakthrough in rocket propulsion, announcing an almost limitless era of space exploration.

David Strorm's father doesn't approve of Angus Morton's unusually large horses, calling them blasphemies against nature. Little does he realise that his own son, his niece Rosalind and their friends have their own secret aberration which would label them as mutants. But as David and Rosalind grow older it becomes more difficult to conceal their differences from the village elders. Soon they face a choice: wait for eventual discovery or flee to the terrifying and mutable Badland.

Belisarius is a quantum man, an engineered Homo quantus who fled the powerful insight of dangerously addictive quantum senses. He found a precarious balance as a con man, but when a client offers him untold wealth to move a squadron of warships across an enemy wormhole, he must embrace his birthright to even try. In fact, the job is so big that he'll need a crew built from all the new sub-branches of humanity. If he succeeds, he might trigger an interstellar war, but success might also point the way to the next step of Homo quantus evolution.

An almost limitless archive of our history lies hidden inside our bodies, and this book traces the ancient story of Scotland from that scientific viewpoint. The mushrooming of genetic studies, of DNA analysis, is rewriting history in spectacular fashion. In Scotland: A Genetic Journey, Alistair Moffat explores the history that is printed on our genes, and in a remarkable new approach, uncovers the detail of where Scots are from, where they have journeyed, and who they are - and in so doing, vividly colors in a DNA map of Scotland.

Alice Roberts uses the latest research to uncover the evolutionary history hidden in all of us, from the secrets found only in our embryos and genes - including why as embryos we have what look like gills - to those visible in your anatomy. This is a tale of discovery, exploring why and how we have developed as we have. This is your story, told as never before.

My name is Rex. I am a good dog.... Rex is also seven feet tall at the shoulder, bulletproof, bristling with heavy-calibre weaponry, and a deadly weapon in a dirty war. He's part of a Multiform Assault Pack operating in the lawless anarchy of Campeche, southeastern Mexico. He has the intelligence to carry out his orders and feedback implants to reward him when he does. All he wants to be is a Good Dog, and to do that he must do exactly what Master says.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

With a vision of a world free from a war, a cat and his human minions set out to change humanity. An epic tale awaits. Follow Braden, Micah, and the Golden Warrior as their adventures take them through the wasteland to the mystical south of Planet Vii.

When Lenina and Bernard visit a savage reservation, we experience how Utopia can destroy humanity. Cloning, feel-good drugs, anti-aging programs, and total social control through politics, programming, and media: has Aldous Huxley accurately predicted our future? With a storyteller's genius, he weaves these ethical controversies in a compelling narrative that dawns in the year 632 A.F. (After Ford, the deity). When Lenina and Bernard visit a savage reservation, we experience how Utopia can destroy humanity.

Francis Saxover and Diana Brackley, two scientists investigating a rare lichen, discover it has a remarkable property: it retards the aging process. Francis, realising the implications for the world of an ever-youthful, wealthy elite, wants to keep it secret, but Diana sees an opportunity to overturn the male status quo by using the lichen to inspire a feminist revolution. As each scientist wrestles with the implications and practicalities of exploiting the discovery, the world comes ever closer to learning the truth.

James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, and agricultural chemistry as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact on our society and our world.

What is human consciousness, and how is it possible? This question fascinates thinking people from poets and painters to physicists, psychologists, and philosophers. From Bacteria to Bach and Back is Daniel C. Dennett's brilliant answer, extending perspectives from his earlier work in surprising directions, exploring the deep interactions of evolution, brains, and human culture.