Showing titles in Genetics

In this groundbreaking approach to the evolution of all life, Richard Dawkins shows how the body, behaviour, and genes of every living creature can be read as a book – an archive of the worlds of its ancestors. A perfectly camouflaged desert lizard has a desiccated landscape of sand and stones ‘painted’ on its back. Its skin can be read as a description of ancient deserts in which its ancestors survived – and, before that, of the worlds of its more remote ancestors: a genetic book of the dead.

What makes you the way you are - and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains.

This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is for every one of the 100 billion modern humans who has ever drawn breath. But it is also our collective story, because in each of our genomes we carry the history of the whole of our species.

Alice Roberts uses the latest research to uncover the evolutionary history hidden in all of us, from the secrets found only in our embryos and genes - including why as embryos we have what look like gills - to those visible in your anatomy. This is a tale of discovery, exploring why and how we have developed as we have. This is your story, told as never before.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

The Apples, Amazons and Googles of the next few decades will be biotech companies. The tech companies of the last few years have changed how we do things but the businesses driving the biotech revolution are about making life better. These companies will solve many of our most intractable problems: cancer, dementia, diabetes, elderly care, mental health challenges, even power generation and agricultural production. Biotech will mean that we can live far better, safer, healthier, wealthier, happier, and longer lives.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

In 1994 Professor Bryan Sykes, a leading world authority on DNA and human evolution, was called in to examine the frozen remains of a man trapped in glacial ice in northern Italy. News of both the Ice Man's discovery and his age, which was put at over 5,000 years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative?

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no-one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable. But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable. In Lifespan, Dr David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that.

Fifty thousand years ago, we were not the only species of human in the world. There were at least four others, including the Neanderthals, Homo floresiensis, Homo luzonesis and the Denisovans. At the forefront of the latter's ground-breaking discovery was Oxford Professor Tom Higham. In The World Before Us, he explains the scientific and technological advancements.

Resistance to malaria. Blue eyes. Lactose tolerance. What do all of these traits have in common? Every one of them has emerged in the last 10,000 years.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

Over 500,000 years ago, a single gene mutated. It spread over time, becoming critical in the journey transforming our earliest ancestors into fully modern humans, capable of navigating the entire planet and beyond. Then just a few thousand years ago, humans gradually outsourced knowledge to writing, and we displaced art and music from the heart of learning. This is the extraordinary story of the discovery of a supergene that makes us uniquely human.

Scientists' understanding of life is progressing more rapidly than at any point in human history, from the extraordinary decoding of DNA to the controversial emergence of biotechnology. Featuring pioneering biologists, geneticists, physicists, and science writers, Life explains just how far we've come - and takes a brilliantly educated guess at where we're heading.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

In An Appetite for Wonder Richard Dawkins brought us his engaging memoir of the first 35 years of his life from early childhood in Africa to publication of The Selfish Gene in 1976, when he shot to fame as one of the most exciting new scientists of his generation. In Brief Candle in the Dark he continues his autobiography, following the threads that have run through the second half of his life so far and homing in on the key individuals, institutions and ideas that inspired and motivated him.

From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.

Humanity has often found itself on the precipice. We've survived and thrived because we've never stopped moving. In this eye-opening book, Johannes Krause, chair of the Max Planck Institute for the History of Humanity, offers a new way of understanding our past, present and future. Marshalling unique insights from archaeogenetics, an emerging new discipline that allows us to read our ancestors' DNA like journals chronicling personal stories of migration, Krause charts two millennia of adaption, movement and survival.

Cancer has always been with us. It killed our hominid ancestors, the mammals they evolved from and the dinosaurs that trampled the ground before that. Tumours grow in pets, livestock and wild animals. Even tiny jelly-like Hydra - creatures that are little more than a tube full of water - can get cancer. Paradoxically, many of us think of cancer as a contemporary killer, a disease of our own making caused by our modern lifestyles.

We are on the cusp of a major transformation in healthcare—yet few people know it. At top hospitals and a few innovative health-tech startups, scientists are working closely with patients to dramatically extend their "healthspan"—the number of healthy years before disease sets in. In The Age of Scientific Wellness, two visionary leaders of this revolution in health take us on a thrilling journey to this new frontier of medicine.